Location & Date

The Solutions Center at Research Triangle Park
1101 Slater Road Durham, NC
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Wed. March 2, 2016
9:30am - 6:00pm

Contact & Other Information

Cindy Rewerts
e-Mail Event Organizer

Price: Regular Members - $88 & Student/Post Doc - $47

  2016 RTP-DMDG Winter Symposium  
Hosted By: Research Triangle Park Drug Metabolism Discussion Group



Wednesday, March 2, 2016, 9:30 am-5:30 pm


" Next Gen Culture: The Future of Cell and Tissue Models in Research, Drug Development and Therapy"


The Solutions Center


Abstract: Cell culture techniques were initially developed in the early 1900’s and advanced significantly in the 1940s and 1950s to support research primarily in virology resulting in life saving vaccines.  Since then advances in purification and isolation techniques for specific cells from organ tissues have resulted in an explosion of cellular tools that have become an integral part in understanding disease and facilitating drug development in both academia and the pharmaceutical industry.  Much of the mainstay of cell culture using continuous cell lines and primary cell cultures, primarily in two dimensions, continue to be invaluable for basic research but is arguably primitive and does not reproduce the anatomy or physiology of a tissue.  So what’s next?  A new generation of cellular techniques are being developed through advanced engineering that allows unprecedented establishment of cellular constructs to meet emerging complex challenges. Augmented with advancements in new scaffolds, 3D printing, co-culturing and microfluidics, such cultures have proven to be closer to in vivo natural systems, thus proving to be useful for many applications. This symposium draws on the experience of visionary scientists that have developed a new generation of cell culture systems that vary widely - and range from constructing complex tissues for disease research, drug development, regenerative medicine and ultimately whole organ construction.  



“Next Gen Culture Models: Applying Nature’s Lessons to In Vitro Approaches”

Ed LeCluyse, PhD

Principal Scientist, LifeNet Health/UNC-IDSS


“Engineering Microscale Co-cultures for Drug Screening and Disease modeling”

Salman Khetani, PhD –

Associate Prof of Bioengineering, University of Illinois Chicago


"3D Bioprinting of Complex, Multi-cellular Tissues and Their Application to In Vitro Modeling "

Sharon Presnell, PhD

 Chief Technology Officer & EVP of R&D, Organovo


"Organs-on-Chips for Advancing Drug Discovery and Precision Medicine”

Geraldine Hamilton, PhD

President and CSO, Emulate


" Regenerative Medicine Applications”

Anthony Atala, MD

Director of the Wake Forest Institute for Regenerative Medicine


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