Location & Date

Merck Research Laboratories
33 Avenue Louis Pasteur, Boston, MA
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Wed. June 12, 2019
8:00 am - 6:00 pm

Contact & Other Information

Sirimas Sudsakorn
e-Mail Event Organizer
Guests: 100 to 500

  2019 Summer Symposium  
Hosted By: New England Drug Metabolism Discussion Group



Way beyond the rule of 5

The future of DMPK in a multimodality world

June 12th, 2019
Merck Research Laboratories

Sponsored by


Morning Session I: Protein Biotherapeutics

Dan Wolak
Scientist, Pharmacokinetics & Drug Metabolism, Amgen


Presents:   "In Vitro and In Vivo ADME of Biotherapeutic Proteins in Discovery and Development/Parallels to SM ADME" 

Enrique Escandon
Senior Principal Scientist, PPDM, Merck

Presents: "
Integrated Fluorescent-Based Approach to Assess the In Vivo Fate of Experimental Biologics"

Jennifer Fretland
Head of DMPK US, Sanofi

Presents: "Biotherapeutics: Use of Modeling and Simulation Approaches for Decision Making"   


Morning Session II: Cellular Therapy


Peter Pieorg
Director, Analytical Design in Cell Therapies, Takeda Pharmaceuticals

Presents: "What is Needed to Support a CART Clinical Trial"


Chelsea Xue
Head of Analytics, Cell Therapy, Takeda Pharmaceuticals

Presents: "Advancing Product Analytics for Cell Therapies"


Afternoon Session I: siRNA/ASO


Brooke Rock
Principal Scientist, Pharmacokinetics & Drug Metabolism, Amgen


Presents: " Transforming Traditional SM ADME Assays to Support the Translation of siRNA Pharmacology from the Benchtop to the Clinic"

Jing-Tao Wu
VP, Early Development, Alnylam Pharmaceuticals


Presents: "The Use of ADME Sciences to Advance RNA Interference Therapeutics"


Xiao Shelley Hu
Director, DMPK and Clinical Pharmacology, Wave Life Sciences


Presents: "Special ADME Considerations in ASO Development"

Afternoon Session II: Gene Therapy/CRISPR

Kate Zhang

VP, Biological Development, Editas Medicine


Presents: "Editas Experience from Discovery to IND Acceptance of the CRISPR Medicine Focusing on the Bioassay"


Poster Information

Submission deadline: June 3rd, 2019

Maximum Poster size: 3’W X 4’H

Please email your poster title and abstract to upendra.argikar@novartis.com by 5 PM, June 3rd, 2019


Continental Breakfast, Registration and Poster Set-Up will begin at 8:00 AM   
Presentations will begin at 8:30 AM

'For further information, email: Sirimas.sudsakorn@sanofi.com'  

Registration/Cancellation Deadline:  5PM June 5th, 2019

If you cannot attend this meeting, but wish to make a donation to NEDMDG - please use the following link:




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